– Harvard’s David Sinclair predicts rejuvenation trials by 2027. – Surge in off-label Rapamycin usage for lifespan extension. – AI reengineers nobel-winning proteins to reverse
Researchers have shown that boosting the brain’s energy-producing mitochondria can reverse memory and motor problems in mice with dementia-like symptoms. Using a tool called mitoDREADD-Gs, scientists proved for the first time that mitochondrial dysfunction is not just linked to but can directly cause neurodegeneration.
This is the first long-term, randomized controlled trial to show that vitamin D can protect telomere length. It suggests that a simple, inexpensive supplement may not just support bone health—but could also help preserve the integrity of our DNA and slow biological aging itself.
Kidney stones affect 12% of people and often recur, leading to repeated surgeries and months of discomfort. Current treatments are slow, painful, or invasive. This approach could offer faster pain relief, fewer surgeries and a safe option for patients who can’t tolerate oral meds
Keratin-based toothpaste offers the first potential solution to permanently repair tooth enamel that was previously considered irreversibly damaged.
This could be the first step toward a broad, fast, and affordable anti-cancer vaccine platform—a game changer compared to today’s slow, hyper-targeted treatments.
reprogramming resets the epigenetic “software” that drifts with age. Do it partially and you keep cell identity but regain youthful function.
Bezos-backed Altos Labs is quietly testing cellular rejuvenation therapies in humans. Here’s the signal from the noise.
An AI + epigenetics test (Chronosense) reports ~2-year accuracy for biological age estimates.
FDA green-lights once-daily aceclidine drops that sharpen near vision for up to 10 hours.
Astaxanthin, spermidine, and NMN+TMG—what they do and where they might fit.
Whey, inulin, and berberine can nudge GLP-1, blunt glucose spikes, and protect lean mass.
Harvard-linked work suggests lithium depletion plays a key role—micro-doses reversed Alzheimer’s-like changes in mice.
Track your biological age, decode your glycans, and personalize your stack.
