Scientists at the Salk Institute report that partial cellular reprogramming using Yamanaka factors can roll back biological age in mice while avoiding tumor formation. This matters because the biggest knock against reprogramming has been cancer risk. The new data suggests a safer path forward—and a potential timeline toward human use.

Why it’s exciting: reprogramming resets the epigenetic “software” that drifts with age. Do it partially and you keep cell identity but regain youthful function.

Read more → Salk Institute · NAD.com summary